mitop_logo home Human Mouse Yeast C.elegans N.crassa

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1. -. -. - OXIDOREDUCTASES.
1. 1. -. -   ACTING ON THE CH-OH GROUP OF DONORS.
1. 1. 1. -     WITH NAD(+) OR NADP(+) AS ACCEPTOR.
1. 1. 1. 1       Alcohol dehydrogenase.
1. 1. 1. 8       Glycerol-3-phosphate dehydrogenase (NAD+).
1. 1. 1.30       3-Hydroxybutyrate dehydrogenase.
1. 1. 1.31       3-Hydroxyisobutyrate dehydrogenase.
1. 1. 1.35       3-Hydroxyacyl-CoA dehydrogenase.
1. 1. 1.37       Malate dehydrogenase.
1. 1. 1.38       Malate dehydrogenase (oxaloacetate decarboxylating).
1. 1. 1.39       Malate dehydrogenase (decarboxylating).
1. 1. 1.40       Malate dehydrogenase (oxaloacetate decarboxylating)(NADP+).
1. 1. 1.41       Isocitrate dehydrogenase (NAD+).
1. 1. 1.42       Isocitrate dehydrogenase (NADP+).
1. 1. 1.86       Ketol-acid reductoisomerase.
1. 1. 1.145       3-beta-Hydroxy-delta5-steroid-dehydrogenase.
1. 1. 1.184       Carbonyl reductase (NADPH).
1. 1. 2. -     WITH A CYTOCHROME AS ACCEPTOR.
1. 1. 2. 3       L-Lactate dehydrogenase (cytochrome).
1. 1. 2. 4       D-Lactate dehydrogenase (cytochrome).
1. 1.99. -     WITH OTHER ACCEPTORS.
1. 1.99. 5       Glycerol-3-phosphate dehydrogenase.
1. 2. -. -   ACTING ON THE ALDEHYDE OR OXO GROUP OF DONORS.
1. 2. 1. -     WITH NAD(+) OR NADP(+) AS ACCEPTOR.
1. 2. 1. 3       Aldehyde dehydrogenase (NAD+).
1. 2. 1. 5       Aldehyde dehydrogenase (NAD(P)+).
1. 2. 1.27       Methylmalonate-semialdehyde dehydrogenase (acylating).
1. 2. 1.38       N-Acetyl-gamma-glutamyl-phosphate reductase.
1. 2. 4. -     WITH A DISULFIDE AS ACCEPTOR.
1. 2. 4. 1       Pyruvate dehydrogenase (lipoamide).
1. 2. 4. 2       Oxoglutarate dehydrogenase (lipoamide).
1. 2. 4. 4       3-Methyl-2-odobutanoate dehydrogease (lipoamide).
1. 3. -. -   ACTING ON THE CH-CH GROUP OF DONORS.
1. 3. 1. -     WITH NAD+ OR NADP+ AS ACCEPTOR.
1. 3. 1.34       2,4-Dienoyl-CoA reductase (NADPH).
1. 3. 3. -     WITH OXYGEN AS ACCEPTOR.
1. 3. 3. 1       Dihydroorotate oxidase.
1. 3. 3. 3       Coproporphyrinogen oxidase.
1. 3. 3. 4       Protoporphyrinogen oxidase.
1. 3. 5. -     WITH A QUINONE OR RELATED COMPOUND AS ACCEPTOR.
1. 3. 5. 1       Succinate dehydrogenase (ubiquinone).
1. 3.99. -     WITH OTHER ACCEPTORS.
1. 3.99. 1       Succinate dehydrogenase.
1. 3.99. 2       Butyryl-CoA dehydrogenase.
1. 3.99. 3       Acyl-CoA dehydrogenase.
1. 3.99. 7       Glutaryl-CoA dehydrogenase.
1. 3.99.10       Isovaleryl-CoA dehydrogenase 
1. 3.99.13       Long-chain-acil-CoA dehydrogenase.
1. 4. -. -   ACTING ON THE CH-NH(2) GROUP OF DONORS.
1. 4. 1. -     WITH NAD(+) OR NADP(+) AS ACCEPTOR.
1. 4. 1. 3       Glutamate dehydrogenase [NAD(P)+].
1. 4. 1. 4       Glutamate deydrogenase (NADP+).
1. 4. 3. -     WITH OXYGEN AS ACCEPTOR.
1. 4. 3. 4       Amine oxydase (flavin-containing).
1. 4. 4. -     WITH A DISULFIDE AS ACCEPTOR.
1. 4. 4. 2       Glycine dehydrogenase (decarboxylating).
1. 5. -. -   ACTING ON THE CH-NH GROUP OF DONORS.
1. 5. 1. -     WITH NAD(+) OR NADP(+) AS ACCEPTOR.
1. 5. 1. 2       Pyrroline-5-carboxylate reductase.
1. 5. 1. 5       Methylenetetrahydrofolate dehydrogenase (NADP+).
1. 5. 1.12       1-Pyrroline-5-carboxylate dehydrogenase.
1. 5. 1.15       Methylenetetrahydrofolate dehydrogenase (NAD+).
1. 5. 5. -     WITH A QUINONE OR SIMILAR COMPOUND AS ACCEPTOR.
1. 5. 5. 1       Electron-transferring-flavoprotein dehydrogenase.
1. 5.99. -     WITH OTHER ACCEPTORS.
1. 5.99. 2       Dimethylglycine dehydrogenase.
1. 6. -. -   ACTING ON NADH OR NADPH.
1. 6. 1. -     WITH NAD+ OR NADP+ AS ACCEPTOR.
1. 6. 1. 1       NAD(P)+ transhydrogenase (B-specific).
1. 6. 2. -     WITH A CYTOCHROME AS ACCEPTOR.
1. 6. 2. 2       Cytochrome-B5 reductase.
1. 6. 5. -     WITH A QUINONE OR SIMILAR COMPOUND AS ACCEPTOR.
1. 6. 5. 3       NADH dehydrogenase (ubiquinone).
1. 6.99. -     WITH OTHER ACCEPTORS.
1. 6.99. 3       NADH dehydrogenase.
1. 8. -. -   ACTING ON A SULFUR GROUP OF DONORS.
1. 8. 1. -     WITH NAD(+) OR NADP(+) AS ACCEPTOR.
1. 8. 1. 4       Dihydrolipoamide dehydrogenase.
1. 8. 3. -     WITH OXIGEN AS ACCEPTOR.
1. 8. 3. 1       Sulfite oxidase.
1. 9. -. -   ACTING ON A HEME GROUP OF DONORS.
1. 9. 3. -     WITH OXYGEN AS ACCEPTOR.
1. 9. 3. 1       Cytochrome-C oxidase.
1.10. -. -   ACTING ON DIPHENOLS AND RELATED SUBSTANCES AS DONORS.
1.10. 2. -     WITH A CYTOCHROME AS ACCEPTOR.
1.10. 2. 2       Ubiquinol--cytochrome C reductase.
1.11. -. -   ACTING ON A PEROXIDE AS ACCEPOR (PEROXIDASES).
1.11. 1. 5       Cytochrome-C peroxidase.
1.11. 1. 7       Peroxidase.
1.14. -. -   ACTING ON PAIRED DONORS WITH INCORPORATION OF MOLECULAR OXYGEN.
1.14.15. -     WITH A REDUCED IRON-SULFUR PROTEIN AS ONE DONOR, AND INCORPORATION OF ONE ATOM OF OXYGEN
1.14.15. 4       Steroid 11beta-monooxygenase.
1.14.15. 6       Cholesterol monooxygenase (side-chain-cleaving).
1.15. -. -   ACTING ON SUPEROXIDE RADICALS AS ACCEPTOR.
1.15. 1. 1       Superoxide dismutase.
1.18. -. -   ACTING ON REDUCED FERREDOXIN AS DONOR.
1.18. 1. -     WITH NAD+ OR NADP+ AS ACCEPTOR.
1.18. 1. 2       Ferredoxin--NADP+ reductase.

2. -. -. - TRANSFERASES.
2. 1. -. -   TRANSFERRING ONE-CARBON GROUPS.
2. 1. 1. -     METHYLTRANSFERASES.
2. 1. 1.17       Phosphatidylethanolamine N-methyltransferase.
2. 1. 1.32       tRNA (guanine-N2-)-methyltransferase.
2. 1. 1.114       Hexaprenyldihydroxybenzoate methyltransferase.
2. 1. 2. -     HYDROXYMETHYL-, FORMYL- AND RELATED TRANSFERASES.
2. 1. 2. 1       glycine hydroxymethyltrnnsferase.
2. 1. 2. 9       METHIONYL-tRNA FORMYLtransferase.
2. 1. 2.10       Aminomethyltransferase.
2. 1. 3. -     CARBOXYL- AND CARBAMOYLTRANSFERASES.
2. 1. 3. 3       Ornithine carbamoyltransferase.
2. 1. 4. -     AMIDOTRANSFERASES.
2. 1. 4. 1       Glycine amidinotransferase.
2. 3. -. -   ACYLTRANSFERASES.
2. 3. 1. -     ACYLTRANSFERASES.
2. 3. 1. 1       Amino-acid N-acetyltransferase.
2. 3. 1. 7       Carnitina O-acetyltransferase.
2. 3. 1. 9       Acetyl-CoA C-acetyltransferase.
2. 3. 1.12       Dihdyrolipoamide S-acetyltransferase.
2. 3. 1.13       Glycine N-acyltransferase.
2. 3. 1.16       Acetyl-CoA C-acyltransferase.
2. 3. 1.21       Carnitina O-palmitoyltransferase.
2. 3. 1.35       Glutamate N-acetyltransferase.
2. 3. 1.37       5-Aminolevulinic acid synthase.
2. 3. 1.41       3-Oxoacyl-[acil-carrier protein] synthase.
2. 3. 1.61       Dihydrolipoamide S-succinyltransferase.
2. 4. -. -   GLYCOSILTRANSFERASES.
2. 4. 2. -     PENTOSYLTRANSFERASES.
2. 4. 2. 4       Thymidine phosphorylase.
2. 5. -. -   TRANSFERRING ALKYL OR ARYL GROUPS, OTHER THAN METHYL GROUPS.
2. 5. 1. -     -.
2. 5. 1. 8       tRNA isopentenyltransferase.
2. 5. 1.15       Dihydropteroate synthase.
2. 5. 1.18       Glutathione transferase.
2. 5. 1.29       Farnesyltranstransferase.
2. 6. -. -   TRANSFERRING NITROGENOUS GROUPS.
2. 6. 1. -     TRANSAMINASES (AMINOTRANSFERASES).
2. 6. 1. 1       Aspartate aminotransferase.
2. 6. 1. 5       Tyrosine transaminase.
2. 6. 1.11       Acetylornithine aminotransferase.
2. 6. 1.13       Ornithine--oxo-acid aminotransferase.
2. 6. 1.19       4-Aminobutyrate aminotransferase.
2. 6. 1.26       Thyroid-hormone transaminase.
2. 6. 1.42       Branched-chain amino acid aminotransferase.
2. 6. 1.44       Alanine--glyoxylate transaminase.
2. 6. 1.51       Serine--pyruvate transaminase.
2. 7. -. -   TRANSFERRING PHOSPHOROUS-CONTAINING GROUPS.
2. 7. 1. -     PHOSPHOTRANSFERASES WITH AN ALCOHOL GROUP AS ACCEPTOR.
2. 7. 1. 1       Hexokinase.
2. 7. 1.30       Glycerol kinase.
2. 7. 1.99       [Pyruvate dehydrogenase (lipoamide)] kinase.
2. 7. 1.113       Deoxyguanosyne kinase.
2. 7. 2. -     PHOSPHOTRANSFERASES WITH A CARBOXYL GROUP AS ACCEPTOR.
2. 7. 2. 8       ACETYLGLUTAMATE kinase.
2. 7. 3. -     PHOSPHOTRANSFERASES WITH A NITROGENEOUS GROUP AS ACCEPTOR.
2. 7. 3. 2       Arginine kinase.
2. 7. 4. -     PHOSPHOTRANSFERASES WITH A phosphate GROUP AS ACCEPTOR.
2. 7. 4. 3       Adenylate kinase.
2. 7. 4.10       Nucleoside-triphosphate--adenylate kinase.
2. 7. 6. -     DIPHOSPHOTRANSFERASES.
2. 7. 6. 3       2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine.
2. 7. 7. -     NUCLEOTIDYLTRANSFERASES.
2. 7. 7. 6       DNA-directed RNA polymerase.
2. 7. 7. 7       DNA-directed DNA polymerase.
2. 7. 7.25       tRNA adenylyltransferase.
2. 7. 7.41       Phosphatidate cytidylyltransferase.
2. 7. 8. -     TRANSFERASES FOR OTHER SUBSTITUTED PHOSPHATE GROUPS.
2. 7. 8. 5       CDPdiacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
2. 7. 8. 8       CDPdiacylglycerol--serine O-phosphatidyltransferase.
2. 8. -. -   TRANSFERRING SULFUR-CONTAINING GROUPS.
2. 8. 1. -     SULFURTRANSFERASES.
2. 8. 1. 1       Thiosulfate sulfurtransferase.
2. 8. 3. -     Co-A TRANSFERASES.
2. 8. 3. 5       3-Oxoacid CoA-transferase.

3. -. -. - HYDROLASES.
3. 1. -. -   ACTING ON ESTER BONDS.
3. 1. 1. -     CARBOXYLIC ESTER HYDROLASES.
3. 1. 1. 4       Phospholipase A2.
3. 1. 2. -     THIOLESTER HYDROLASES.
3. 1. 2. 6       Hydroxyacylgluatathione hydrolase.
3. 1. 3. -     PHOSPHORIC MONOESTER HYDROLASES.
3. 1. 3.12       Trehalose-phosphatase.
3. 1. 3.16       Phosphoprotein phosphatase.
3. 1.26. -     ENDORIBONUCLEASES PRODUCING 5'-PHOSPHOMONOESTERS.
3. 1.26. 5       Ribonuclease P.
3. 4. -. -   ACTING ON PEPTIDE BONDS (PEPTIDE HYDROLASES).
3. 4.21. -     SERINE ENDOPEPTIDASES.
3. 4.21.92       Endopeptidase Clp.
3. 4.24. -     METALLOENDOPEPTIDASES.
3. 4.24.37       Saccharolysin.
3. 4.24.59       Mitochondrial intermediate peptidase.
3. 4.24.64       Mitochondrial processing peptidase.
3. 5. -. -   ACTING ON CARBON-NITROGEN BONDS, OTHER THAN PEPTIDE BONDS.
3. 5. 4. -     IN CYCLIC AMIDINES.
3. 5. 4. 9       Methenyltetrahydrofolate cyclohydrolase.
3. 6. -. -   ACTING ON ACID ANHYDRIDES.
3. 6. 1. -     IN PHOSPHOROUS-CONTAINING ANHYDRIDES.
3. 6. 1. 1       Inorganic pyrophosphatase.
3. 6. 1.23       dUTP pyrophosphatase.
3. 6. 1.34       H(+)-transporting ATP synthase.
3. 6. 1.36       Hydrogen/potassium-exchanging ATPase.

4. -. -. - LYASES.
4. 1. -. -   CARBON-CARBON LYASES.
4. 1. 1. -     CARBOXY-LYASES.
4. 1. 1. 9       Malonyl-CoA decarboxylase
4. 1. 1.32       Phosphoenolpyruvate carboxykinase (GTP).
4. 1. 1.65       Phosphatidylserine decarboxylase.
4. 1. 2. -     ALDEHYDE-LYASES.
4. 1. 2.15       2-Dehydro-3-deoxyphosphoheptonate aldolase.
4. 1. 2.25       Dihydroneopterin aldolase.
4. 1. 3. -     OXO-ACID-LYASES.
4. 1. 3. 4       Hydroxymethylglutaryl-CoA lyase.
4. 1. 3. 5       Hydroxymethylglutaryl-CoA synthase.
4. 1. 3. 7       Citrate (si)-synthase.
4. 1. 3.12       2-Isopropylmalate synthase.
4. 1. 3.18       Acetolactate synthase.
4. 1.99. -     OTHER CARBON-CARBON LYASES.
4. 1.99. 3       Deoxyribodipyrimidine photolyase.
4. 2. -. -   CARBON-OXYGEN LYASES.
4. 2. 1. -     HYDRO-LYASES.
4. 2. 1. 1       Carbonate dehydratase.
4. 2. 1. 2       Fumarate hydratase.
4. 2. 1. 3       Aconitate hydratase.
4. 2. 1. 9       Dihydroxy-acid dehydratase.
4. 2. 1.16       Threonine dehydratase.
4. 2. 1.17       Enoyl-CoA hydratase.
4. 2. 1.36       Homoaconitate hydratase.
4. 2. 1.75       Uroporphyrinogen-III synthase.
4. 4. -. -   CARBON-SULFUR LYASES.
4. 4. 1.17       Holocytochrome-C synthase.
4.99. -. -   OTHER LYASES.
4.99. 1. 1       Ferrochelatase.

5. -. -. - ISOMERASES.
5. 1. -. -   RACEMASES AND EPIMERASES.
5. 1.99. -     ACTING ON OTHER COMPOUNDS.
5. 1.99. 4       ????
5. 2. -. -   CIS-TRANS-ISOMERASES.
5. 2. 1. 8       Peptidylprolyl isomerase.
5. 3. -. -   INTRAMOLECULAR OXIDOREDUCTASES.
5. 3. 3. -     TRANSPOSING C==C GROUPS.
5. 3. 3. 1       Steroid delta-isomerase.
5. 3. 3. 8       Dodecenoyl-CoA delta-isomerase.
5. 4. -. -   INTRAMOLECULAR transferaseS (MUTASES).
5. 4.99. -     TRANSFERRING OTHER GROUPS.
5. 4.99. 2       Methylmalonyl-CoA mutase.

6. -. -. - LIGASES.
6. 1. -. -   FORMING CARBON-OXYGEN BONDS.
6. 1. 1. -     LIGASES FORMING AMINOACYL-tRNA AND RELATED COMPOUNDS.
6. 1. 1. 1       Tyrosine--tRNA ligase.
6. 1. 1. 2       Tryptophan--tRNA ligase.
6. 1. 1. 3       Threonine--tRNA ligase.
6. 1. 1. 4       Leucine--tRNA ligase.
6. 1. 1. 5       Isoleucine--tRNA ligase.
6. 1. 1. 6       Lysine--tRNA ligase.
6. 1. 1. 9       Valine--tRNA ligase.
6. 1. 1.10       Methionine--tRNA ligase.
6. 1. 1.12       Aspartate--tRNA ligase.
6. 1. 1.17       Glutamate--tRNA ligase.
6. 1. 1.19       Arginine--tRNA ligase.
6. 1. 1.20       Phenylalanine--tRNA ligase.
6. 1. 1.21       Histidine--tRNA ligase.
6. 1. 1.22       Asparagine--tRNA ligase.
6. 2. -. -   FORMING CARBON-SULFUR BONDS.
6. 2. 1. -     ACID--THIOL LIGASES.
6. 2. 1. 1       Acetate--CoA ligase.
6. 2. 1. 3       Long-chain-fatty-acid--CoA ligase.
6. 2. 1. 4       succinate--CoA ligase (GDP-forming).
6. 3. -. -   FORMING CARBON-NITROGEN BONDS.
6. 3. 2. -     ACID--AMINO-ACID LIGASES (PEPTIDE SYNTHASES).
6. 3. 2.17       Folylpolyglutamate synthase.
6. 3. 4. -     OTHER CARBON--NITROGEN LIGASES.
6. 3. 4. 3       Formate--tetrahydrofolate ligase.
6. 3. 4. 9       Biotin--[methylmalonyl-CoA-carboxyltransferase] ligase.
6. 3. 4.10       Biotin--[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase.
6. 3. 4.11       Biotin--[methylcrotonoyl-CoA-carboxylase] ligase.
6. 3. 4.16       Carbamoyl-phosphate synthase (ammonia).
6. 3. 5. -     CARBON--NITROGEN LIGASES WITH GLUTAMINE AS AMIDO-N-DONOR.
6. 3. 5. 5       Carbamoyl-phosphate synthase (glutamine-hydrolysing).
6. 4. -. -   FORMING CARBON-CARBON BONDS.
6. 4. 1. 1       Pyruvate carboxylase.
6. 4. 1. 3       Propionyl-CoA carboxylase.

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